abbyphillips5432 abbyphillips5432
  • 14-03-2018
  • Chemistry
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Two major organic products are formed in the reaction of p-chlorotoluene with sodium amide. draw the structure of both products.

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ChemistryHelper2024
ChemistryHelper2024 ChemistryHelper2024
  • 27-03-2018
Amide ion is a very strong base that makes a nucleophilic aromatic substitution reaction, but here the aryl halide lacks an electron-withdrawing substituent. so the reaction occurs via elimination-addition sequence, not addition-elimination reaction by removal of H proton and Cl with the formation of triple bond (Benzyne) then addition of NH₃ in which NH₂ may be added on the same site as Cl or the site we removed H from it

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